Tylenol (or generic acetaminophen) – regular or extra strength is the safest painkiller in pregnancy. Avoid combinations of Tylenol with other painkillers like Excedrin. We avoid NSAIDs like ibuprofen (Motrin, Advil) Aleve and full strength aspirin (325 mg) in pregnancy. Baby aspirin (81 mg) can be given to pregnant women but it’s too low a dose for pain.
Local anesthetics (without epinephrine), Extra Strength Tylenol and additional pain medications are sometimes used but you should review these medicines with your OB/Gyn before taking them, such as if you are scheduled for dental work.