A Reproductive Endocrinology and Infertility (REI) specialist confirms the diagnosis of PCOS and checks for hormone problems or low egg supply. Semen analysis and a Hysterosalpingogram (HSG) to check for blocked tubes are good tests to do as well. Treatment may start with metformin (insulin sensitizers) with or without ovulation inducing tablets like Clomid or letrozole. Some women need IVF (In Vitro Fertilization) if simpler treatments aren’t working, or rarely low-dose shots to induce ovulation.